Pathophysiology of postoperative pain

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Persistent Postoperative Pain: Pathophysiology, Risk Factors, and Prevention.

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Migraine is a primary episodic headache disorder characterized by a cascade of events that involve various combinations of neurologic, gastrointestinal and autonomic changes. Headache is probably caused by activation of meningeal and blood vessel nociceptors combined with an alteration in central pain modulation. Headache and its associated neuro-vascular changes are subserved by the trigeminal...

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In addition to the ethical and humanitarian reasons for minimizing pain and suffering is the recognition that both physiologic and pathophysiologic responses to poorly controlled pain may have deleterious effects on postsurgical outcomes. Consequences may be particularly serious in elderly and critically ill populations. In these individuals, pathophysiologic responses to large incisions, exten...

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Pathophysiology of Pain.

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Pathophysiology of pain.

Pain occurring at the end of life is often a complex amalgam of symptoms that arise from neuropathic, somatic, and visceral pain syndromes. Likewise, the stimuli from which the pain syndromes originate are complex and may include inflammatory, neuropathic, and ischemic components. The palliative management of pain is further complicated by nociceptor sensitization that often occurs in chronic p...

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ژورنال

عنوان ژورنال: Pain

سال: 2011

ISSN: 0304-3959

DOI: 10.1016/j.pain.2010.11.005